RxSafeCheckWhat's Safe Tgether? Open the free tool

Understand how your medicines work together.

"What's Safe Together?"

RxSafeCheck is a free, private tool that helps you see how your prescriptions, over-the-counter medicines, supplements, and even food may interact — organized by the part of the body they affect. Learn what to watch for and bring the right questions to your pharmacist or doctor.

Why we exist

Our mission & vision

Our mission is to help patients, caregivers, and families better understand medication safety, treatment complexity, and the questions they should ask their healthcare teams. Through RxSafeCheck™, we provide clear, accessible information that supports safer conversations between patients, physicians, pharmacists, specialists, and caregivers. We do not replace medical advice, diagnose conditions, or recommend treatments — we help people become better prepared, better informed, and better equipped to take part in decisions about their care.

Our vision is a healthcare world where every patient has the knowledge, confidence, and support needed to ask the right questions about medications, diagnoses, treatment changes, side effects, drug interactions, and risks.

What's Safe Together?

Safe Together is the belief that safer healthcare happens when patients, caregivers, and medical teams communicate openly and work as one team.

RxSafeCheck was built by a physician and a biomedical scientist whose personal experience shaped this mission. After losing his father to prostate cancer — following more than nine years of changing diagnoses, new medications, new treatments, emergency room visits, and complex medication interactions — he saw firsthand how difficult it can be for families to navigate modern healthcare. His father was fortunate to have a son with experience in public health and physiology, and access to a network of healthcare providers and experts. Most patients and families do not have that same support.

That is why RxSafeCheck™ was created — not to tell patients what treatment to choose, but to help patients and caregivers understand what questions to ask their doctors, pharmacists, nurses, and specialists. It's a conversation tool, not a diagnosis or treatment tool, helping identify topics worth discussing: medication interactions, side effects, treatment changes, chronic drug exposure, acute reactions, and risks that deserve closer attention.

Because safety is not something patients should have to figure out alone. Safety happens when patients, caregivers, and medical teams are informed, prepared, and safe together.

Made for real life

Built for patients, caregivers, and families

Patients & seniors

Keep every medicine in one place and understand interactions in plain language — no jargon, no account required.

Caregivers & families

Manage a loved one's medicines, spot warning signs, and prepare for appointments with printable summaries.

Anyone starting a new medicine

Before you fill a new prescription, see what to ask your pharmacist and what to watch for.

Why this matters

Medication safety is one of healthcare's quietest, most serious problems

Adverse drug events — including drug interactions, side effects, and dosing errors — are among the most common preventable harms in medicine. Most are never dramatic; they build quietly, one prescription at a time. Understanding your own medicines, and asking the right questions, is one of the simplest ways to lower that risk.

2.7M+

Hospitalized patients in the U.S. experience an adverse drug event each year, by one widely cited estimate.

~80,000

U.S. drug-overdose deaths in 2024 — down about 27% from 2023, but still a leading cause of death for adults 18–44 (CDC).

~600,000

Deaths worldwide each year are attributed to psychoactive drug use, most involving opioids (WHO).

Beyond overdoses, some patient-safety advocates argue that adverse drug events, taken together, rank among the leading causes of death in the U.S. — a claim that is debated among researchers, but one that reflects a real and under-recognized burden. Older adults and people taking several medicines at once carry the highest risk, which is exactly where a clear medication list and good questions help most.

Sources: U.S. Centers for Disease Control and Prevention (National Vital Statistics System, 2024 provisional overdose data); World Health Organization (opioid overdose fact sheet); American Society of Pharmacovigilance; peer-reviewed literature on adverse drug events. Figures are estimates from public sources and are provided for general awareness, not as medical or statistical advice. RxSafeCheck is educational and does not diagnose or treat.

How we're different

Built for you — not for clinicians, and not for advertisers

Most interaction checkers were built as clinical reference tools or drug encyclopedias, with the checker added later. They're powerful, but they're written for professionals, often show ads inside your results, and treat safety as a one-time lookup. RxSafeCheck takes a different approach: plain language, no ads, no tracking, and a place to understand your whole picture over time.

What matters to patients & caregiversRxSafeCheckTypical checkers
Plain language, written for patientsYesOften clinical
No ads inside your resultsYesOften ads
No account or login requiredYesSometimes
Results grouped by body systemYesRarely
Conditions, food & travel — not just drug-drugYesRarely
Questions to bring to your care teamYesRarely
Large professional drug databaseGrowingExtensive

We're honest about the tradeoff: long-established checkers cover a larger drug list, and for an exhaustive professional lookup they're excellent. RxSafeCheck focuses on the well-established, high-impact interactions — and explains them in a way you can actually use, then points you to your pharmacist to confirm. Different jobs, done well.

Simple by design

How it works

Add your medicines

Search prescriptions, OTC medicines, supplements, and food factors. Scan a bottle or barcode if you like.

See how they interact

Results are grouped by the part of the body they affect, with clear explanations and severity flags.

Talk to your pharmacist

Get ready-made questions and a printable summary to bring to your pharmacist or prescriber.

Try it free →

Educational, honest, and private

We built RxSafeCheck to help you learn and start conversations — not to replace your healthcare team.

  • Not medical advice. RxSafeCheck is educational. It does not diagnose, prescribe, or replace your pharmacist or doctor.
  • Private by default. Your medication list stays in your browser for the session only — no account required, and we do not sell your data or use advertising trackers.
  • Grounded in public sources. Built on well-established pharmacology and public resources like the U.S. National Library of Medicine (RxNorm, DSLD) and ClinicalTrials.gov.
  • "Nothing found" isn't a guarantee. The knowledge base is curated, not exhaustive — always confirm with your pharmacist.

Learn

Popular medication-safety guides

Plain-language articles on the questions people ask most. Educational only — always confirm with your pharmacist or prescriber.

Interactions & safety

Using your medicines

Pharmacy, caregiving & reviews

Or jump straight to the free tool →

New

RxSafeTravel™ — plan safer trips with your conditions & medicines

Travel disrupts routines — time zones, missed doses, heat, altitude, long flights, new foods, and care away from home. For people managing chronic conditions or several medications, small disruptions can become real concerns. RxSafeTravel™ helps you get ready by organizing the health and medication information worth discussing with your care team before you go.

Answer a few questions about your trip, conditions, and medicines, and RxSafeTravel builds a personalized set of questions for your doctor, pharmacist, and travel-medicine clinician — plus pre-, during-, and post-travel checklists, an emergency card, and a printable plan. It's a conversation tool, not medical advice.

"Know before you go. Plan before problems happen. Travel safer together."

Educational planning tool — it does not diagnose, recommend treatment, or confirm medication legality. Always verify with official sources and your healthcare team.

Start travel planning →

Live · across the web

Latest health & medication headlines

Real, current headlines pulled live from official U.S. government and research sources — FDA drug recalls, ClinicalTrials.gov, and PubMed. Educational only; always confirm with your pharmacist or the official source.

Loading the latest headlines…
Fetching FDA recalls, clinical trials, and research…

Headlines refresh automatically. Want the full interactive feed with filters and search? Open the News Hub in the app →

For pharmacies, senior care & caregiver organizations

Share a trusted, ad-free medication-safety resource with the people you serve — or explore co-branded checklists and partnerships.

Contact us about partnering
Important: RxSafeCheck is an educational tool and does not provide medical advice, diagnosis, or treatment. Always consult a qualified pharmacist or prescriber about your medicines, and call your local emergency number for emergencies. In the U.S., reach Poison Control at 1-800-222-1222.